| Fiscal period | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
| Period End Date | 12/31/2025 | 12/31/2024 | 12/31/2023 | 12/31/2022 | 12/31/2021 | 12/31/2020 | 12/31/2019 | 12/31/2018 | 12/31/2017 | 12/31/2016 |
| Net Sales | 65,179.00 | 45,042.70 | 34,124.10 | 28,541.40 | 28,318.40 | 24,539.80 | 22,319.50 | 24,555.70 | 22,871.30 | 21,222.10 |
| Total Revenues | 65,179.00 | 45,042.70 | 34,124.10 | 28,541.40 | 28,318.40 | 24,539.80 | 22,319.50 | 24,555.70 | 22,871.30 | 21,222.10 |
| Cost of sales | 11,052.00 | 8,418.30 | 7,082.20 | 6,629.80 | 7,312.80 | 5,483.30 | 4,721.20 | 6,430.00 | 6,070.20 | 5,654.90 |
| Gross Profit | 54,127.00 | 36,624.40 | 27,041.90 | 21,911.60 | 21,005.60 | 19,056.50 | 17,598.30 | 18,125.70 | 16,801.10 | 15,567.20 |
| Research and development | 13,337.00 | 10,990.60 | 9,313.40 | 7,190.80 | 7,025.90 | 6,085.70 | 5,595.00 | 5,307.10 | 5,281.80 | 5,243.90 |
| Acquired in-process research and development | 2,910.00 | 3,280.40 | 3,799.80 | 908.50 | 874.90 | 660.40 | 239.60 | 1,983.90 | 1,112.60 | 30.00 |
| Marketing and administrative | 11,094.00 | 8,593.80 | 7,403.10 | 6,440.40 | 6,431.60 | 6,121.20 | 6,213.80 | 6,631.80 | 6,588.10 | 6,452.00 |
| Asset impairments, restructuring and other special charges | (484.00) | (860.60) | (67.70) | (244.60) | (316.10) | (131.20) | (575.60) | (482.00) | (1,673.60) | (382.50) |
| Interest expense | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Asset impairments, restructuring, and other special charges | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other income (expense) - Special | (571.00) | (218.60) | 96.70 | (320.90) | (201.60) | 1,171.90 | 291.60 | 74.80 | 52.40 | (84.80) |
| Total Non Operating income (expense) | 39,448.00 | 32,362.30 | 27,569.50 | 21,735.00 | 22,162.90 | 17,309.90 | 17,053.60 | -- | 20,673.90 | 17,848.10 |
| Income (loss) before income taxes | 25,731.00 | 12,680.40 | 6,554.60 | 6,806.40 | 6,155.50 | 7,229.90 | 5,265.90 | 3,795.70 | 2,197.40 | 3,374.00 |
| Current- Federal | -- | 3,312.00 | 3,017.90 | 2,153.60 | 938.50 | 567.60 | 280.20 | (54.30) | (100.60) | (57.00) |
| Current- State | 4,639.00 | 31.20 | 24.30 | 45.50 | (28.40) | (47.30) | (14.40) | 9.70 | 4.00 | (125.00) |
| Current- Foreign | 2,159.00 | 1,430.30 | 613.00 | 547.70 | 466.00 | 650.40 | 299.80 | 80.00 | 38.50 | 378.90 |
| Deferred- Federal | -- | (2,178.70) | (2,369.00) | (1,992.40) | (977.50) | (97.40) | 141.30 | 64.00 | 801.50 | 517.00 |
| Deferred- State | (1,149.00) | (31.30) | (6.20) | (114.60) | 0.60 | (20.50) | (54.80) | 3.40 | 0.40 | 5.80 |
| Deferred- Foreign | (558.00) | (473.10) | 34.20 | (78.20) | 174.60 | (16.60) | (24.10) | 285.60 | (256.30) | (83.30) |
| Deferred: Unremitted earnings to be repatriated due to change in tax law | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Income taxes | 5,091.00 | 2,090.40 | 1,314.20 | 561.60 | 573.80 | 1,036.20 | 628.00 | 563.70 | 2,401.50 | 636.40 |
| Current- 2017 Tax Act - provisional | -- | -- | -- | -- | -- | -- | -- | 201.50 | 3,247.50 | -- |
| Deferred- 2017 Tax Act - provisional | -- | -- | -- | -- | -- | -- | -- | (26.20) | (1,333.50) | -- |
| Income from continuing operations before extraordinary item | -- | -- | -- | -- | 5,581.70 | 6,193.70 | 4,637.90 | -- | -- | -- |
| Net income from discontinued operations | -- | -- | -- | -- | -- | -- | 3,680.50 | -- | -- | -- |
| Income Before Extraordinary Income & Accounting Change | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Extraordinary item | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Cumulative effect of a change in accounting principle, net of tax | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Net income (loss) attributable to common shareholders | 20,640.00 | 10,590.00 | 5,240.40 | 6,244.80 | 5,581.70 | 6,193.70 | 8,318.40 | 3,232.00 | (204.10) | 2,737.60 |
| Earnings (loss) Per Share (Basic) - Cont Ops | -- | -- | -- | -- | 6.15 | 6.82 | 4.98 | -- | -- | -- |
| Earnings (loss) per share Discontinued operations (Basic) | -- | -- | -- | -- | -- | -- | 3.95 | -- | -- | -- |
| EPS (Basic) - Cumulative effect of a change in accounting principle | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings (loss) per share (Basic) - Extras | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings (loss) per share (Basic) | 23.00 | 11.76 | 5.82 | 6.93 | 6.15 | 6.82 | 8.93 | 3.14 | (0.19) | 2.59 |
| Earnings (loss) Per Share (Diluted) - Cont Ops | -- | -- | -- | -- | 6.12 | 6.79 | 4.96 | -- | -- | -- |
| Earnings (loss) per share discontinued operations (Diluted) | -- | -- | -- | -- | -- | -- | 3.93 | -- | -- | -- |
| EPS (Diluted) - Cumulative effect of a change in accounting principle | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings (loss) per share (Diluted) - Extras | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings (loss) per share (Diluted) | 22.95 | 11.71 | 5.80 | 6.90 | 6.12 | 6.79 | 8.89 | 3.13 | (0.19) | 2.58 |
| Weighted Average Shares Outstanding (Basic) | 897.30 | 900.61 | 900.18 | 901.74 | 906.96 | 907.63 | 931.06 | 1,027.72 | 1,052.02 | 1,058.32 |
| Weighted Average Shares Outstanding (diluted) | 899.30 | 904.06 | 903.28 | 904.62 | 911.68 | 912.51 | 935.68 | 1,033.67 | 1,052.02 | 1,061.83 |